Abstract The World Health Organization published the preferred product characteristics for a Group A Streptococcus (Strep A) vaccine in 2018.Based on these parameters for the age of vaccination, vaccine efficacy, duration of protection black rose globe from vaccine-derived immunity, and vaccination coverage, we developed a static cohort model to es
Background: Chemokines are a family of proteins mainly mediating the homing and migration of various cells.The CXC chemokine CXCL12 is a member of low-weight-molecular chemokines.In the kidney, CXCL12 is pivotal for renal development and exerts a modulatory effect in kidney diseases under different etiologic settings by binding with CXC chemokine r
Background: Patients with proliferative lupus nephritis are at risk of frequent relapses.Whether low- dose prednisone prevents relapses is uncertain.Objectives: We undertook a pilot RCT to determine the feasibility of a larger trial.Design: Pilot randomized controlled trial.Setting: Single center Canadian outpatient nephrology clinic.Patients: Part
Abstract Predictive factors for response to regorafenib in recurrent glioblastoma, IDH-wildtype, are scarcely recognized.The objective of this study was to identify molecular predictive factors for response to regorafenib using a clinically available platform.We analyzed a prospective cohort of 30 patients harboring recurrent glioblastoma, IDH-wild
Humanitarian emergencies often result in population displacement and increase the risk for transmission of communicable diseases.To address the increased risk for outbreaks during humanitarian emergencies, the World Health Organization developed the Early Warning Alert and Response Network (EWARN) for early detection of epidemic-prone diseases.The